New Histamine Beginners Guide

The Beginner's Guide to Histamine Intolerance by [Joneja, Janice]   This time, not one of my books! Dr Janice Joneja (her of the really useful Histamine Intolerance Q&A you can see on my histamine section here) has brought out a new Beginner’s Guide which I read and reviewed last week.

I thought it was great and will be very useful when people ask me: ‘Is it HIT (histamine intolerance), allergy or MCAS?’ I shall say: read this and then come back to me!

Available as an e-book here on Amazon UK, here on Amazon US.  And you can see my mini review of it here.

Meantime, here is the intro blurb to start you off, well done Janice!

A distillation of her years of research and experience in a really easy-to-understand format – complete with suggestions for a low histamine diet.
‘For the first time in this long, exhausting, lonely journey, I finally feel like I’ve been pointed in the right direction to find answers and wellness! Thank you Dr. Joneja!!’

If you’re struggling with your health, but the doctor can’t find anything actually wrong with you, then perhaps you have Histamine Intolerance. It’s a condition with a range of unpleasant symptoms, which can include headaches, flushing, itching, hives, swollen facial tissues, racing heart, digestive problems, irritability and more.

Many doctors don’t know much about Histamine Intolerance, although it’s estimated that 1% of the world’s population suffers from it. If you’re one of them, you’ll know first-hand how distressing and frustrating the disorder can be.

Dr Janice Vickerstaff Joneja saw the misery that this condition caused sufferers, and made it the focus of her research work; she’s been studying the condition and helping patients since the 1990s.

She’s now created this easy-to-read guide—which will help you understand if you have Histamine Intolerance, and what you can do about it—with clear advice and explanations, lots of interesting real-life cases, plus diet and treatment recommendations.

If you wonder if your symptoms could be caused by Histamine Intolerance—or if you believe they are and want to know what to do about it—this book is for you.

DAO Histamine Intolerance Products: Is ARG Stronger or Not?

A few months ago, Allergy Research Group released a welcome new DAO enzyme product for helping people with histamine intolerance.

(If you don’t know about histamine intolerance and what I am talking about, do read my article Could It Be Histamine?

The product caused much confusion (with me and a few of you anyway!) because of the dosage differences with other more established products.

DAO Histaminase™ With Bioflavonoids 60 Capsules

Anyway, the label shows it has 41mg of Diamine Oxidase in it. This sounded very strong as the one I usually recommend is Sciotec’s DAOSin, which contains 4.2mg per capsule:

DAOSiN can 90 capsules

This seemed very odd, so I thought I would look into it. Several months later (!), I have finally got to the bottom of it. It’s all in the way they say it on the label apparently. Here’s my conversation for you (or one of the many..)..

In effect, two ARG capsules equals 1 Sciotec! Got there with my nagging in the end!

If you open the capsules there are little beads inside, they are called pellets.
the pellets are the coated DAO
in our capsules we have 81mg Pellets
and this 81mg Pellets deliver 9000-10000 HDU
they [ARG]state on their Label 41 mg DAO (Daosin)
with 5000 HDU
so they give the weight of the Daosin pellets, they buy from us
practically, their product delivers only half of one of our Daosin capsules
You are saying that in reality, a capsule contains 2.1mg as opposed to your 4.2mg, correct?[me]
Yes right. This is the weight of the Protein extract from the porcine kidney with 7% DAO
So you have in their capsule 41mg Daosin pellets with 2.1mg Protein extract with 7% DAO
And in yours…?[me]
81mg Dao Pellets and 126mg Vitamine C. 4.2mg Protein extract with 7% DAO
It is best to look
at the HDU
histamine degrading unit
the higher the HDU the more histamine is broken down
Hope that makes some sense and allays the confusion!

Histamine Intolerance Triggered By Hormone Change?

Interesting article on histamine intolerance causing panic and anxiety today for you.

Histamine, anxiety and panic attacks

That’s helpful in itself, isn’t it, but whilst I was reading it, I picked up the fact that histamine intolerance is commonly triggered at peri-menopause, right when the hormone levels are changing yet again. This does fit in with my clinical experience that it is mostly women over about 50 who have it, but I have also seen it happen after having babies and breast-feeding as well as during puberty. Of course, men’s hormones also change at puberty and during so-called andropause, which might also explain the timing of their own developing histamine issues.

So why, two years ago, did these symptoms suddenly appear, apparently out of the blue? The answer lies in the information you provided in response to my further question: you are now 50 years of age. Two years ago you likely entered peri-menopause, or menopause, and your hormone levels, especially oestrogen and progesterone, changed dramatically. As a result, the histamine controls in your body were affected, and you developed histamine intolerance.

Does that fit in with the start of your symptoms maybe? Might be worth a think, then, if so, check your hormone levels and correct them, not forgetting your adrenals, which start to have a lot more influence on hormone production after about 40.

A clue? Hope it helps for you.

Histamine and DAO Tests Upgrade

Just a quickie to let you know that I have now managed to get one lab to do both whole blood/urine histamine and DAO (diamine oxidase) levels which will make life easier for those tracking their histamine intolerance.

We have been using Biolab for some time now for the body levels of histamine and they have recently upgraded their methodology along new research lines apparently, consequently the price has gone up. Still, I would rather we had the most efficient tests with viable results than tests that don’t help, wouldn’t you? Actually, they went up months ago and I held them down for you, but needs must now as both have gone up.

They have also started offering the diamine oxidase test so, actually, when I priced both up, it wasn’t that far off my price would be using two different labs. So, I have decided to do both tests through Biolab now. If for some reason you still want your DAO tests done by BTS, our previous lab for this, that’s fine; just ask. I really want to stay with BTS but it is simply more practical to have one lab sending your test kits out and for you to have to send them back to one lab so practicality wins out.  I have combined the two tests into a discounted Histamine Intolerance Test here for you to make life easier and that bit cheaper, too, so hope that helps.

For more info on histamine intolerance generally, do read the article I wrote here: Could It Be Histamine?

With body histamine testing, you can now do either blood or urine; both are just as viable and urine is easier, of course :). DAO is still blood.

Hope that helps.


Could It Be #Histamine?

Yay – my latest article has just been published by the lovely FoodsMatter people. This time, I am looking at a more unusual type of food sensitivity – histamine intolerance or, actually to be more precise: histamine excess.

Take a look.

Could it be histamine?
Nutritionist Micki Rose looks at the symptoms, possible causes and ways to diagnose and treat histamine ‘intolerance’/excess


#Histamine Intolerance: Guest Post

Just to let you know, an interview I gave about histamine intolerance has just been published on the Low Histamine Chef blog so go and take a peek if you like.


I did actually say several times that I  can no way be called an expert on histamine issues and I have a long way to go with learning about it, but I gave my take on it anyway. The blog editor, Yasmina, decided to remove the stuff about me not being an expert, but I am telling you that anyway as some of you will know more about it than I do!

Hope it is of some help. Useful site to visit anyway if you suffer with or suspect histamine problems.

Interestingly, the lab who does the DAO histamine test for us has been teasing me that they have some more research/info on histamine and the gut to share with us soon. They are having a conference in Germany next week so I hope to find out more then. Look forward to it!

#Histamine Intolerance: Updated Histamine Tests

Just to let you know that today I have updated the Histamine Intolerance tests by combining both whole blood histamine and level of the DAO enzyme needed to break histamine down into one test. You can still get the whole histamine and DAO tests separately too if you need them.

For anyone who suspects histamine intolerance, it is best to check both blood levels and the DAO enzyme levels. This is because you could have a normal level of blood histamine BUT if your DAO enzyme levels are low, you would get the symptoms of histamine intolerance. People think they need to see high blood histamine on tests and rule out a histamine problem if levels show normal – but that could be misleading if the DAO enzymes are low. The new histamine intolerance test just makes life that bit easier – and cheaper as I have discounted it slightly for you too 🙂

Here’s some info on histamine intolerance from Allergy UK:

What is histamine intolerance?

Put simply this is an imbalance of histamine and the enzyme DAO, Diamine Oxydase (sic) in the body.  For someone with histamine Intolerance,  this deficiency means that they are unable  to break down ingested histamine quickly enough.

The consequence: Ingested histamine is broken down significantly slower and accumulates within the body. The body then reacts to the accumulated histamine with similar symptoms as for allergies, for example, with rashes, itching, headaches, diarrhoea and vomiting or abdominal pain.    It is important to know however that this does not point to an allergy, but to intolerance.